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4 associated genes
16 signs/symptoms

PROTEIN INTERACTIONS: 3

Hypohidrotic ectodermal dysplasia with immunodeficiency

2 OMIM references -
2 associated genes
No signs/symptoms info

MALT lymphoma

Hypohidrotic ectodermal dysplasia with immunodeficiency

BIRC3	(UniProt - OMIM)		IKBKG	(UniProt - OMIM)
FOXP1	(UniProt - OMIM)		NFKBIA	(UniProt - OMIM)
IGH	(UniProt)
MALT1	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MALT1 BIRC3 MALT1	(0.86) (0.84) (0.63)	IKBKG IKBKG NFKBIA

Citations in the biomedical literature:

MALT lymphoma		Hypohidrotic ectodermal dysplasia with immunodeficiency
	Synonym(s): - Extranodal marginal zone B-cell lymphoma - MALToma - Mucosa-associated lymphatic tissue lymphoma - Mucosa-associated lymphoid tissue lymphoma		Synonym(s): - Anhidrotic ectodermal dysplasia with immunodeficiency - EDA-ID - HED-ID

	Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare immune disease - Rare skin disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: normal Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: child / adolescent Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 2 OMIM references - No MeSH references

MALT lymphoma
	Very frequent - Asthenia / fatigue / weakness - Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis - Fever / chilling - Hematologic / blood / lymphatic cancer - Hyperhidrosis / increased sweating - Lung / pulmonary infiltrates - Nausea / vomiting / regurgitation / merycism / hyperemesis - Weight loss / loss of appetite / break in weight curve / general health alteration Frequent - Constipation Occasional - Acute abdominal pain / colic - Chronic uveitis / blepharitis / episcleritis / scleritis / conjonctivitis / keratitis - Defect / anomaly of lacrimal system - Lymphadenopathy / polyadenopathies - Mediastinal / hilar adenopathies - Repeat respiratory infections - Thyroid anomalies
Hypohidrotic ectodermal dysplasia with immunodeficiency
(no data available)